In the Pipeline
As of December 31, 2011

Bristol-Myers Squibb's pipeline is one of the most innovative in the industry. Learn more about the medicines we are developing.


Exploratory Development
(Post discovery through Phase II)
Full Development (Registrational program) Marketed Product Development (Approved in at least one major market)
EGFR/IGFR Tandem Adnectin (oncology) Brivanib (oncology) YERVOY™ (ipilimumab)
(oncology)
Pegdinetanib
(VEGF R-2 Adnectin)
(oncology)
Elotuzumab (oncology) SPRYCEL® (dasatinib)
(oncology)
Anti-CD70 ADC (oncology) Necitumumab (oncology) ERBITUX® (cetuximab)
(oncology)
JAK2 Inhibitor (oncology) Dapagliflozin (metabolics) IXEMPRA® (ixabepilone) (oncology)
IGF-1R Antagonist (oncology) Apixaban (cardiovascular) ONGLYZA® (saxagliptin) KOMBIGLYZE XR™ (saxagliptin and metformin HCL extended-release) (metabolics)
SMO Antagonist (oncology) Daclatasvir (NS5A inhibitor)(virology) NULOJIX®(belatacept) (immunology)
IL-21 (oncology) ORENCIA® (abatacept) (immunology)
Anti-KIR (oncology) BARACLUDE® (entecavir) (virology)
Urelumab (Anti-CD137) (oncology) REYATAZ® (atazanavir sulfate) (virology)
Notch Inhibitors (oncology) SUSTIVA® (efavirenz) ATRIPLA® (efavirenz / emtricitabine / tenofovir disoproxil fumarate) (virology)
Anti-PD1 (oncology) ABILIFY® (neuroscience)
Anti-CXCR4 (oncology)
Anti-LAG3 (oncology)
PEG-FGF21 (metabolics)
11βHSD Inhibitors (metabolics)
TGR5 agonist (metabolics)
FGF21-PKE Adnectin (metabolics)
GPR119 Agonists (metabolics)
CCR1 Antagonists (immunology)
Anti-IP10 (immunology)
Anti-CD28 (immunology)
Anti-IL6 (immunology)
IL-23 Adnectin (immunology)
Anti-IL31 (immunology)
Anti-CD40L (immunology)
LPA1 Antagonist (immunology)
LXR Modulators (cardiovascular)
PCSK9 Adnectin (cardiovascular)
CCR2 / 5 Antagonists(cardiovascular)
IKACh Inhibitors (cardiovascular)
IKur Antagonists(cardiovascular)
Peginterferon lambda-1a (virology)
Asunaprevir (NS3 Inhibitor) (virology)
NS5B Inhibitor (virology)
HIV Attachment Inhibitor (virology)
Anti-PD-L1 (virology)
NRT Inhibitor (virology)
HIV Maturation Inhibitor (virology)
NS5B Primer Grip Inhibitor (virology)
NS5A Second Generation (virology)
NS5B Site 1 Inhibitor (virology)
α-7 Nicotinic Agonist (neuroscience)
Aβ Modulator (neuroscience)
Triple Reuptake Inhibitors (neuroscience)
Microtubule Stabilizer (neuroscience)
Avagacestat (Gamma Secretase Inhibitor) (neuroscience)
GABA/Nicotinic Modulator (neuroscience)
CGRP Antagonist (neuroscience)
Please click on product name to see the Full Prescribing Information for ABILIFY®, ATRIPLA®, BARACLUDE®, ERBITUX®, IXEMPRA®, ONGLYZA™, ORENCIA®, REYATAZ®, SPRYCEL®, SUSTIVA®, including boxed WARNINGS for ABILIFY®, ATRIPLA®, BARACLUDE®, ERBITUX®, IXEMPRA™, and NULOJIX®, and Boxed WARNING for YERVOY™ regarding immune-mediated adverse reactions.

Exploratory Development compounds are investigational drugs that are post discovery through Phase II.

Full Development compounds are investigational drugs that are in late-stage clinical development, or have been submitted to regulatory agencies for approval.

Marketed Product Development compounds have been approved in at least one major market and are among approved medicines that are driving current and future growth while continuing their clinical development to determine whether additional indications and formulations will benefit patients.

Like any other scientific endeavor, clinical testing of novel drug compounds is a complex, time-consuming, resource-intensive process with no guaranteed results. But, as described here, Bristol-Myers Squibb is committed to pursuing such clinical development and, in doing so, to bringing new hope to patients.